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The overall picture for the Senate then is that the Democrats should win Virginia, Wisconsin and Massachusetts to give them 52 seats. There are enough reasons to doubt Republican chances in Indiana and Nevada to suggest a Democrat might win one of those states, leaving a 53-47 majority.
But this is a Presidential election year, where Senate races are not as safe to call as in off-Presidential campaigns where the candidates stand or fall a bit more on their own merits. Republican faith in their theory of a lacklustre Democratic turnout may be nothing but a fantasy, but until the results start to confirm Obama's lead in the polls as reality, then Democrats face the possibility of losing the Senate as well as the White House. It is unlikely, but stranger results have happened in recent American political history.